CHRONIC OSTEOMYELITIS OSTEOMYELITIS Chronic osteomyelitis is difficult to eradicate completely. Systemic symptoms may subside, but one or more foci in the bone may contain purulent material, infected granulation tissue, or a sequestrum (Fig. 16-10). Intermittent acute exacerbations may occur for years and often respond to rest and antibiotics. The hallmark of chronic osteomyelitis is infected dead … Continue reading CHRONIC OSTEOMYELITIS

SUBACUTE HEMATOGENOUS OSTEOMYELITIS HEMATOGENOUS OSTEOMYELITIS Compared with acute osteomyelitis, subacute hematogenous osteomyelitis has a more insidious onset and lacks the severity of symptoms, which makes the diagnosis of this disorder difficult. Subacute osteomyelitis is relatively common. Because of the indolent course of subacute osteomyelitis, diagnosis typically is delayed for more than 2 weeks. Systemic signs and symptoms … Continue reading SUBACUTE HEMATOGENOUS OSTEOMYELITIS

ACUTE HEMATOGENOUS OSTEOMYELITIS HEMATOGENOUS OSTEOMYELITIS·    most common type of bone infection, usually in children, males in all age groups affected·   caused by a bacteremia, which is a common occurrence in childhood. The causes of bacteremia are many. Bacteriological seeding of bone generally is associated with other factors such as localized trauma, chronic illness, malnutrition, or an inadequate … Continue reading ACUTE HEMATOGENOUS OSTEOMYELITIS


OSTEOMYELITISOsteomyelitis is defined as an inflammation of the bone caused by an infecting organism. The infection may be limited to a single portion of the bone or may involve numerous regions, such as the marrow, cortex, periosteum, and the surrounding soft tissue. The infection generally is due to a single organism, but polymicrobial infections can … Continue reading Osteomyelitis

Bone Graft Substitute Materials

Bone Graft Substitute MaterialsAuthor: Cato T Laurencin, MD, PhD, Van Dusen Chair Professor of Academic Medicine, Distinguished Professor of Orthopaedic Surgery, and Chemical, Materials, and Biomolecular Engineering, University of ConnecticutCoauthor(s): Yusuf Khan, PhD, Assistant Professor of Research, Departments of Orthopedic Surgery and Biomedical Engineering, University of Virginia School of MedicineUpdated: Dec 3, 2009IntroductionMore than 500,000 bone graft procedures are … Continue reading Bone Graft Substitute Materials

Teriparatide ( Recombinant human PTH ) effectiveness in Osteoporosis treatment

Teriparatide, Recombinant human PTH (rh PTH [1-34]), which has an identical sequence to the 34 N-terminal amino acids of human PTH.Osteoporosis is defined by the World Health Organization as a T-score of -2.5. T-score is the value compared to control subjects who are at their peak bone mineral density, while Z-score reflects a value compared … Continue reading Teriparatide ( Recombinant human PTH ) effectiveness in Osteoporosis treatment